Table 1.
Demographics and Participant Characteristics
| All Participants (N=75) | Participants With LSTa (n=37) | Participants Without LSTa (n=38) | |
|---|---|---|---|
| Age, years, mean (SD) | 34.1 (10.7) | 33.7 (10.7) | 34.4 (10.9) |
| Female, n (%) | 61 (81.3) | 27 (73.0) | 34 (89.5) |
| Time since idiopathic hypersomnia diagnosis, years, n (%) | |||
| <2 | 12 (16.0) | 5 (13.5) | 7 (18.4) |
| 2–4 | 34 (45.3) | 20 (54.1) | 14 (36.8) |
| 5–9 | 18 (24.0) | 8 (21.6) | 10 (26.3) |
| ≥10 | 11 (14.7) | 4 (10.8) | 7 (18.4) |
| Patient-reported sleep duration, mean (SD) | |||
| Approximate hours of sleep in a typical 24-hour period | 11.6 (3.4) | 14.3 (2.7) | 8.9 (1.1) |
| Approximate hours of sleep in a typical night | 8.9 (1.6) | 9.8 (1.7) | 8.0 (0.8) |
| Approximate hours of sleep in a typical day | 2.7 (2.8) | 4.5 (2.9) | 0.9 (1.0) |
| Participants who took off-label medications for idiopathic hypersomnia, n (%) | 67 (89.3) | 36 (97.3) | 31 (81.6) |
| Current comorbidity (≥5%)b n (%) | |||
| Any psychiatric disorderc | 33 (44.0) | 16 (43.2) | 17 (44.7) |
| Anxiety | 26 (34.7) | 13 (35.1) | 13 (34.2) |
| Major depressive disorder | 9 (12.0) | 2 (5.4) | 7 (18.4) |
| Bipolar disorder or any psychotic disorder | 6 (8.0) | 5 (13.5) | 1 (2.6) |
| Hypothyroidism | 6 (8.0) | 4 (10.8) | 2 (5.3) |
| PTSD | 5 (6.7) | 3 (8.1) | 2 (5.3) |
| Restless legs syndrome | 5 (6.7) | 3 (8.1) | 2 (5.3) |
| Other disorder that may be associated with excessive daytime sleepiness or fatigued | 5 (6.7) | 1 (2.7) | 4 (10.5) |
| Anxiety and PTSD | 4 (5.3) | 3 (8.1) | 1 (2.6) |
Notes: aLong sleep was defined as ≥11 hours of sleep in a 24-hour period (self-reported). bAll comorbidities were self-reported. A participant could have had ≥1 comorbidity. Only comorbidities reported by ≥5% of participants are listed. cThese included anxiety, major depressive disorder, bipolar disorder, or any other psychotic disorders. dThese included 1 person each who had depression; mild depression, possible attention-deficit disorder (but could be sleep disorder); persistent depressive disorder; small fiber neuropathy; and inflammatory bowel disease.
Abbreviations: LST, long sleep time; PTSD, post-traumatic stress disorder; SD, standard deviation.