Table 3–

Characteristics of subjects that were noted to follow commands during subsequent encounters and did not follow commands at hospital discharge.

Subject	Clinical scenario	Arrest details	Arrest etiology	CTH GWR	SSEP	MRI radiologist interpretation	Discharge disposition and exam	Time to commands
1	26-year-old man with history of opioid use disorder found in bed unresponsive.	No bystander CPR, PEA initial rhythm, 14 minutes CPR, 5 mg epinephrine and 1 shock.	Toxicological	NA	NA	Diffusion restriction of cortical white matter of all lobes as well as dentate nuclei and the lentiform nuclei. Unclear if result of heroin inhalation vs. anoxic changes.	Long term acute care. No response to painful stimuli	155 days
2	55-year-old woman with history of hypothyroidism complained of shortness of breath, then collapsed in front of family.	Witnessed collapse, bystander CPR, asystolic initial rhythm, 37 minutes CPR, 7 mg epinephrine, 8 shocks.	Structural heart disease	NA	Present N20 response	Diffusely abnormal gyral edema and restricted diffusion compatible with severe hypoxic ischemic injury, also involving the caudate nuclei.	Long term acute care. Tracked examiner but fid not follow commands.	3 yrs & 2 months Noted following commands at well patient visit. Discharge from long term acute care to brain injury rehab is not in health system.
3	65-year-old man with history of schizophrenia and atrial fibrillation had a witnessed shaking episode and became unresponsive in front of family.	Witnessed collapse, bystander CPR, aystolic initial rhythm, 16 minutes CPR, 3 mg epinephrine, 3 shocks.	Unknown, inconclusive workup but presumed seizure with unclear cause	1.36	NA	No territorial infarct or evidence of diffuse anoxic brain injury.	Long term acute care. Startles but does not track or follow commands	21 days
4	67-year-old woman with history of hypertension pulled off road while driving and collapsed in view of bystanders.	Witnessed collapse, bystander CPR, VT/VF initial rhythm, 28 minutes CPR, 3 mg epinephrine, 6 shocks.	Acute coronary syndrome	1.44	Present N20 response	Cortical edema and gyriform restricted diffusion in the bilateral parietal, medial frontal, and posterior temporal lobes consistent with hypoxic ischemic injury.	Long term acute care. Tracked examiner but did not follow commands.	39 days
5	19-year-old man with no medical history fell and was pinned by bulldozer, with concomitant TBI and polytrauma.	Witnessed trauma, bystander CPR, VT/VF initial rhythm, 5 minutes CPR, 0 mg epinephrine, 1 shock.	Tension pneumothorax	1.29	Absent N20 response	Bilateral decompressive craniectomies with unchanged herniation of the brain through the surgical defects. Findings consistent with diffuse axonal injury corresponding to grade II given the involvement of the corpus callosum.	Acute rehabilitation. Startles but does not track or follow commands	198 days