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. 2022 Dec 21;130(5):868–877. doi: 10.1017/S0007114522003944

Table 2.

Effect of infant nutritional supplementation on neurodevelopment outcomes at 12 months of age

Mean difference (95 % CI)
Modest-protein group (n 388) High-protein group (n 372) No-supplement group (n 374) Modest-protein group v. no-supplement group (Ref) High-protein group v. no-supplement group (Ref) High-protein group v. modest-protein group (Ref)
Mean SD Mean SD Mean SD Mean difference 95 % CI Mean difference 95 % CI Mean difference 95 % CI
BSID composite scores
  Cognitive 105·3 10·0 105·1 10·0 104·2 11·3 1·09 –0·44, 2·61 0·91 –0·63, 2·45 –0·18 –1·60, 1·25
  Motor 95·7 8·4 94·9 9·1 94·2 8·9 1·52 0·28, 2·75* 0·77 –0·53, 2·06 –0·75 –1·99, 0·49
  Language 95·6 8·4 94·8 8·6 94·6 8·9 1·02 –0·22, 2·26 0·22 –1·04, 1·49 –0·80 –2·01, 0·42
  Socio-emotional 98 7·5 96·6 7·0 97·1 7·9 0·88 –0·22, 1·97 –0·53 –1·60, 0·55 –1·40 –2·43, −0·37
Infant temperament
  Total infant temperament scores 109·2 9·7 111·2 10·4 111·9 10·9 –2·76 –4·23, −1·29 –0·71 –2·24, 0·82 2·05 0·62, 3·48

BSID, Bayley Scales of Infant and Toddler Development; CI, confidence interval.

*

Statistically significant at P < 0·05.

Statistically significant at P < 0·01.