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. 2023 May 2;98(5):571–579. doi: 10.1016/j.abd.2022.10.009

Table 2.

Histopathological clues for suspected cutaneous metastases58

Presence of neoplastic cells within lymphatic or blood vessels.
Nodules located in the reticular dermis and/or hypodermis without contact with the epidermis (grenz zone).
Presence of neoplastic cells lined up between collagen fibers (“single filing”)