Table 1.
Patient demographics in normotensive HIV negative (N−ve); normotensive HIV positive (N+ve); Early-onset PE/HIV negative (EOPE−ve); Early-onset PE/HIV positive (EOPE+ve); Late-onset PE/HIV negative (LOPE−ve) and Late-onset PE/HIV positive (LOPE+ve) pregnant women
| Total n = 180 | N−ve | N+ve | EOPE−ve | EOPE +ve | LOPE −ve | LOPE+ve | p value and Dunn’s Multiple comparison | |
|---|---|---|---|---|---|---|---|---|
| n = 30 | n = 30 | n = 30 | n = 30 | n = 30 | n = 30 | |||
|
Maternal Age (years) |
25 (22–30) |
28 (25–31) |
23 (20–27) |
32 (25–37) |
23 (19–26) |
28 (25–34) |
<0.0001 N+ve vs. LOPE−ve EOPE−ve vs. EOPE+ve EOPE−ve vs. LOPE+ve EOPE+ve vs. LOPE-ve LOPE−ve vs. LOPE+ve |
**** * ** * *** ** |
| Weight (kg) |
73.70 (63.25–97.77) |
67.30 (55.25–85.38) |
67.20 (60.25–91.00) |
81.00 (68.48–87.90) |
66.00 (55.75–81.00) |
85.35 (69.90–95.25) |
0.0221 LOPE−ve vs. LOPE+ve |
* * |
|
Systolic Pressure (mmHg) |
111.0 (106.0–116.8) |
111.0 (105.0–117.0) |
151.0 (143.0–160.0) |
148.0 (136.0–161.0) |
154.0 (146.5–173.0) |
145.0 (141.8–153.3) |
<0.0001 N−ve vs. EOPE−ve N−ve vs. EOPE+ve N−ve vs. LOPE−ve N−ve vs. LOPE+ve N+ve vs. EOPE−ve N+ve vs. EOPE+ve N+ve vs. LOPE−ve N+ve vs. LOPE+ve |
**** **** **** **** **** **** **** **** **** |
| Diastolic Pressure (mmHg) |
71.00 (64.50–79.00) |
70.00 (64.00–76.00) |
95.50 (91.00–104.3) |
92.00 (90.00–98.00) |
101.0 (94.00–108.0) |
96.00 (91.00–98.25) |
<0.0001 N−ve vs. EOPE−ve N−ve vs. EOPE+ve N−ve vs. LOPE-ve N−ve vs. LOPE+ve N+ve vs. EOPE−ve N+ve vs. EOPE+ve N+ve vs. LOPE−ve N+ve vs. LOPE+ve |
**** **** **** **** **** **** **** **** **** |
| Gestational weight (kg) |
3.150 (2.975–3.585) |
3.100 (2.600–3.550) |
2.100 (1.625–2.538) |
1.900 (1.300–2.500) |
3.000 (2.723–3.213) |
2.900 (2.300–3.120) |
<0.0001 N−ve vs. EOPE−ve N−ve vs. EOPE+ve N+ve vs. EOPE−ve N+ve vs. EOPE+ve EOPE−ve vs. LOPE−ve EOPE−ve vs. LOPE+ve EOPE+ve vs. LOPE−ve |
**** **** **** **** *** **** * ** |
| Gestational Age (weeks) |
38.00 (37.00–39.00) |
37.00 (36.00–39.00) |
33.00 (30.00–35.00) |
30.00 (25.75–34.50) |
35.50 (34.00–37.00) |
35.00 (33.00–36.00) |
<0.0001 N−ve vs. EOPE−ve N−ve vs. EOPE+ve N−ve vs. LOPE−ve N−ve vs. LOPE+ve N+ve vs. EOPE−ve N+ve vs. EOPE+ve N+ve vs. LOPE−ve N+ve vs. LOPE+ve |
**** **** **** **** **** **** **** * ** |
Key: Results are represented as the median (IQR), *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001
Across the population group (n = 180), the Kruskal–Wallis (K-W) test detected significance for maternal age (p < 0.0001), weight (p = 0.0221), systolic and diastolic pressure (p < 0.0001), and gestational weight and age (p < 0.0001). The Dunn’s multiple comparison test further calculated significance between the PE groups stratified by HIV, indicated in Table 1
Bold values denote significant p values