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Comparison of HBs and HEPs derived from isogenic DC iPSCs. (A) Comparison of global gene expression in HBs and HEPs by PCA of transcriptome profiles (n = 4). (B) GSEA of differentially expressed genes between mutant and corrected in HB and HEPs. Gray shows enrichment in mutant HBs or HEPs; red shows enrichment in corrected HBs or HEPs. (C) Heatmaps showing differences in gene expression within indicated gene sets during hepatic differentiation. Cor, corrected; Mut, mutant.
