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. 2023 Aug 7;11:48. doi: 10.1186/s40635-023-00536-0

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© The Author(s) 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 3 — Prevalence of amino acid substitutions and deletions in Spike RBD in BA.2, BA.4/BA.5, and BQ.1.1-related group viral sequences; The percentage of detected mutations (amino acid substitutions and deletions) per group is displayed on the y-axis, relative to the original Omicron BA.2 reference sequence (SARS-CoV-2/human/USA/FL-CDC-STM-77CPCCUR3/2022). Other individual NTD (N-terminal domain) mutations include H49Y, W64R, M153I, M177L, I197T, Del211, L212I, A222S, T250I, P251H, V289I and S316F; other S1/RBD mutations include N354K, I358L, T376S, T547K, T572I and N568S; other S2 mutations include T547K, T572I, H625R, A642G, A647V, E654K, N658S, N856S, V963F, A1020S, T1117I, P1143L, E1144Q and S1249P