Table II.
Summary of dermatologic manifestations
Case 1 | Case 2 | Case 3 | Case 4 | Case 5 | Case 6 | Case 7 | Case 8 | |
---|---|---|---|---|---|---|---|---|
Average day of rash development (d) | 27 | 36 | 29 | 36 | 186 | 22 | 42 | 57 |
Rash morphology | Maculopapular, non-blanching confluent rash, macules coalescing into patches, some fine scaling | Scaly scattered macules and papules | Generalized macular rash, desquamation, a few bullae |
Diffuse erythematous to dusky macules and papules |
Erythematous maculopapular rash, some morbilliform, a few hyperpigmented macules and papules | Erythematous macules and papules with superficial scaling, coalescing over flanks | Erythematous morbilliform, punctate rash | Perifollicular, morbilliform eruption, numerous purpuric lesions on legs |
Sites involved | Chest, abdomen, back, a few lesions on legs | Face, ears, chest, abdomen, back, extremities (upper > lower) | Generalized, BSA>90%, worse on lower abdomen, lower back, face, palms and soles | Chest, abdomen, back and extremities | Chest, back, proximal arms, thighs, legs, palms and soles | Lower abdomen, suprapubic area, bilateral medial thighs, legs, lateral neck, upper chest, left flank | Chest, abdomen, back and proximal extremities with fewer lesions on distal extremities, palms and soles | Chest, abdomen, back, arms, legs |
Mucosal involvement | No | No | Ulcers -oral mucosa, tongue | No | No | No | No | No |
Pruritus | Yes | No | No | No | Yes | No | No | No |