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. 2023 May 25;299(7):104863. doi: 10.1016/j.jbc.2023.104863

Figure 6.

Figure 6

Structure of the LpgDΔN active site. A, a dihydrogen phosphate ion is found in the LpgDΔN active site (PDB ID: 8GHH). B, the active site of BsGlpQ (PDB ID: 5T9C) with the glycerol-3-phosphate product (cyan) and calcium ion (green). C, an overlay of the active sites of BsGlpQ (grey) and LpgDΔN (yellow) with the manganese ion modeled at the same location as calcium in BsGlpQ. The three active site residues mutated in LpgDΔN (Glu78, His93 and His51) are highlighted. The structures were rendered with PyMOL (version 2.5.1, Schrödinger, LLC) with the hydrogen bonds depicted as dashed red lines.