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. 2023 Jul 13;26(8):107391. doi: 10.1016/j.isci.2023.107391

Table 3.

Frequencies of HLA alleles in patients with LEV-SCARs and LEV-tolerant controls

HLA genotype Carrier, No. (%)
P Odd ratio (95% CI)
LEV-SCAR patients, (n = 12) Tolerant controls, (n = 100)
B∗13:01 4 (33.3) 10 (10.0) 0.043 4.5 (1.15–17.65)
B∗13:02 6 (50.0) 14 (14.0) 7.21 × 10−3 6.14 (1.73–21.76)
Serotype B13 10 (83.3) 22 (22.0) 4.85 × 10−5 17.73 (3.61–86.95)

Abbreviations: CI, confidence interval; LEV, levofloxacin; LEV-SCARs, levofloxacin-induced severe cutaneous adverse drug reactions; OR, odds ratio.