. 2023 Jun 5;102(8):102842. doi: 10.1016/j.psj.2023.102842

Table 5.

Effects of dietary supplementation of ARE on expression of lipid metabolism-related genes in broilers.

		Treatments				Statistics
Tissues	Gene¹	0% ARE	0.15% ARE	0.30% ARE	SEM²	P_anova	P_linear	P_quadratic
Liver	Fatty acids synthesis
	SREBP-1c	1.00	0.90	0.83	0.06	0.535	0.275	0.889
	SCD1	1.00	0.52	0.72	0.11	0.230	0.317	0.161
	FAS	1.00^a	0.34^b	0.62^ab	0.11	0.033	0.111	0.030
	ACC	1.00^a	0.25^b	0.36^b	0.12	0.012	0.016	0.050
	ELOVL6	1.00^a	0.75^ab	0.43^b	0.10	0.045	0.014	0.823
	Fatty acids uptake
	CD36	1.00^b	1.92^a	2.24^a	0.18	0.006	0.002	0.325
	APOA1	1.00^b	2.79^a	2.54^a	0.24	0.001	0.003	0.017
	APOB	1.00	0.95	0.89	0.07	0.822	0.540	0.951
	Fatty acids breakdown
	PPARα	1.00^b	3.43^a	3.15^a	0.39	0.009	0.011	0.051
	ATGL	1.00^c	5.75^a	3.56^b	0.54	<0.001	0.002	0.051
	CPT1	1.00^b	4.91^a	2.79^ab	0.64	0.034	0.202	0.020

Adipose	Fatty acids synthesis
	SREBP-1c	1.00^a	0.31^b	0.52^b	0.10	0.010	0.027	0.019
	SCD1	1.00^a	0.31^b	0.24^b	0.10	0.001	0.001	0.069
	FAS	1.00	0.56	0.73	0.09	0.155	0.235	0.121
	ACC	1.00^a	0.42^b	0.42^b	0.10	0.009	0.007	0.099
	ELOVL6	1.00^a	0.23^b	0.41^b	0.13	0.035	0.049	0.069
	Fatty acids uptake
	CD36	1.00^b	2.15^ab	3.89^a	0.44	0.017	0.005	0.714
	FATP	1.00^b	3.96^a	4.60^a	0.62	0.029	0.013	0.313
	FABP	1.00^b	3.41^a	3.64^a	0.39	0.004	0.003	0.118
	Fatty acids breakdown
	PPARα	1.00^b	3.43^a	3.15^a	0.39	0.009	0.011	0.051
	ATGL	1.00^c	3.87^a	2.46^b	0.34	<0.001	0.022	<0.001
	CPT1	1.00^b	4.91^a	2.79^ab	0.64	0.034	0.202	0.020

^a,b,c

Means within a row with different superscripts are different at P < 0.05.

Abbreviations: ACC, acetyl-CoA carboxylase; APOA1, apolipoprotein A1; APOB, apolipoprotein B; ATGL, adipose triglyceride lipase; CD36, fatty acid transferase; CPT-1, carnitine palmitoyltransferase 1; ELOVL6, fatty acid elongase 6; FABP, fatty acid-binding protein; FAS, fatty acid synthase; FATP, fatty acid transporter; PPARα, peroxisome proliferator-activated receptor-α; SCD1, stearoyl-CoA desaturase-1; SREBP-1c, sterol regulatory element binding protein 1.

SEM = standard error of mean, n = 6–8.