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. 2023 Jul 24;14:1238503. doi: 10.3389/fphar.2023.1238503

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Copyright © 2023 Gómez-Herrera, Patlán, Estrada-Garrido, Hernández-Cruz and Luis.

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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BL-1249 does not affect the endogenous potassium currents or RMP of HEK-WT cells. (A, B) representative family of endogenous K⁺ currents in HEK-WT cells in control and the presence of 100 μM BL-1249, respectively. (C) I-V relationship of HEK-WT currents in control (black circles) and the presence of BL-1249 (100 μM; red circles) (n = 10). (D) Representative current-clamp recording of RMP in HEK-WT cells in the presence of BL (100 μM). (E) The average effect of BL on the RMP of HEK-WT cells in control, in the presence of BL, and during the washout (n = 6).