TABLE 6.
Different ADRs among five anti-TNFα drugs.
| System organ classes | Adalimumab | Infliximab | Etanercept | Golimumab | Certolizumab pegol |
|---|---|---|---|---|---|
| Blood and lymphatic system disorders | Myelosuppression | ||||
| Cardiac disorders | Heart valve incompetence | Acute coronary syndrome | Cardiac valve disease | Sinus tachycardia | |
| Congenital, familial, and genetic disorders | Type IV hyperlipidemia | Gilbert’s syndrome, congenital foot malformation, and hemophilia | VACTERL syndrome | Osteogenesis imperfecta | Clinodactyly |
| Endocrine disorders | Acromegaly | ||||
| Eye disorders | Swelling of the eyelid and blepharospasm | ||||
| Gastrointestinal disorders | Toothache | ||||
| Pregnancy, puerperium, and perinatal conditions | Placenta previa | Induced labor | Twin pregnancy and placenta previa | ||
| Metabolism and nutrition disorders | Reduced fluid intake | Hypomagnesemia | Type 1 diabetes mellitus | Hypovolemia | |
| Immune system disorders | Iodine allergy |