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. 2023 Feb 3;10(6):2597–2613. doi: 10.1016/j.gendis.2023.01.005

Figure 5.

Fig. 5

The cellular communication network between satellite cells (SCs), fast muscle cells (FMCs), and slow muscle cells (SMCs). (A) Bar plot displaying statistically significant ligand-receptor pairs in the three stages. (B) Bar plot demonstrating the proportions of the three stages in distinct signaling pathways. (C) Venn diagram demonstrating the intersection of skeletal muscle disease-related genes, DEGs in SCs, and genes related to ligand-receptor pairs. (D) Chord diagram presenting the distribution of the number of disease-related ligand-receptor pairs among SCs, FMCs, and SMCs in different stages. (E) Doughnut charts showing the proportions of three types of ligand-receptor pairs in the different stages. (F) Bubble plot depicting the specific distribution of statistically significant ligand-receptor pairs among SCs, FMCs, and SMCs. We focused on Dag1-related ligand-receptor interaction pairs. (G) UMAP (uniform manifold approximation and projection) plots indicating signaling pathway groups. The colors represent signaling pathway clusters; the shapes represent stages. The shape sizes are related to the communication probability of the signaling pathways.