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. 2023 Jul 24;17:1186025. doi: 10.3389/fnins.2023.1186025

Table 1.

Demographic and clinical characteristics of study participants.

Subgroups of RVO
Clinical variables Control RVO CRVO BRVO p values
N = 19 N = 20 N = 6 N = 14 BRVO vs. CRVO
Age (mean ± SD) years 66.63 ± 5.29 59.55 ± 11.44 *, a 60.17 ± 11.04 59.29 ± 12.00 *, c 1.000
Male (%)b 52.6 60.00 16.67 50.00 0.163
Hypertension (%)b 42.10 55.00 16.66 71.43 0.111
Diabetes (%)b 10.50 10.00 16.66 7.14 0.515
Smoking (%)b 26.30 15.00 16.66 14.29 0.891
BMI (mean ± SD) kg/m2 22.13 ± 3.58 24.83 ± 3.21 23.7 ± 2.62 25.32 ± 3.40 1.00
BCVA (mean ± SD) 0.93 ± 0.85 0.92 ± 0.28 0.97 ± 0.24 0.90 ± 0.31 1.000
RVO duration (≤ 1-month) (%)b \ 50 50 50 1.000
CRT (mean ± SD) μm 222.22 ± 25.91 588.85 ± 221.26 **, a 660.50 ± 215.33 **, c 558.14 ± 224.35 **, c 0.56
FAZ (mean ± SD) mm2 \ 0.24 ± 0.14 0.23 ± 0.13 0.24 ± 0.15 0.966
PERIM (mean ± SD) mm \ 1.93 ± 0.57 2.05 ± 0.58 1.89 ± 0.58 0.582
ILM-IPL (mean ± SD) \ 125.82 ± 96.88 169.11 ± 121.79 107.26 ± 82.33 0.199
SVD (mean ± SD) \ 44.75 ± 3.77 44.57 ± 3.21 44.82 ± 4.09 0.894
DVD (mean ± SD) \ 44.63 ± 3.23 45.91 ± 2.68 44.08 ± 3.37 0.255

aIndependent sample t-test, between controls and RVO patients; bChi-square test; cOne-way ANOVA test analyzed controls, CRVO, and BRVO patients. *p < 0.05; **p < 0.01. Bold indicating p value was statistically significant. RVO, retinal vein occlusion; BRVO, branch retinal vein occlusion; CRVO, central retinal vein occlusion; BMI, body mass index; BCVA, best corrected visual acuity (expressed as LogMAR); CRT, central retinal thickness; FAZ, foveal avascular zone; PERIM, perimeter of fovea; ILM-IPL, inner limiting membrane-inner plexiform layer; SVD, superficial vessel density; and DVD, deep vessel density.