Table 4.
Correlation between inflammatory factors and BCVA and OCTA parameters in aqueous humor RVO patients (n = 19).
| Variables | Log MAR | CRT | FAZ | PERIM | ILM-IPL | SVD | DVD |
|---|---|---|---|---|---|---|---|
| r | r | r | r | r | r | r | |
| IL-17E | 0.12 | −0.12 | 0.45 | 0.20 | −0.11 | −0.02 | 0.15 |
| Flt-3 L | −0.02 | 0.34 | −0.32 | 0.04 | 0.57 ** | 0.19 | 0.12 |
| IL-3 | −0.25 | 0.42 | 0.24 | 0.11 | 0.39 | −0.13 | 0.14 |
| IL-8 | −0.06 | 0.27 | −0.44 | −0.04 | 0.41 | 0.01 | 0.12 |
| IL-33 | 0.04 | 0.36 | 0.05 | 0.12 | 0.53 * | 0.35 | 0.41 |
| MIP-3β | 0.11 | 0.24 | −0.27 | −0.14 | −0.01 | 0.11 | −0.69 ** |
| MIP-1α | −0.23 | 0.41 | 0.23 | 0.16 | 0.32 | −0.12 | 0.34 |
| GRO β | −0.07 | 0.54 ** | −0.29 | −0.06 | 0.50 ** | 0.22 | −0.08 |
| PD-L1 | 0.12 | 0.36 | 0.19 | 0.16 | 0.55 ** | −0.07 | 0.31 |
| CD40 L | 0.42 | 0.10 | −0.09 | 0.01 | −0.00 | −0.00 | 0.10 |
| IFN-β | −0.35 | 0.19 | 0.03 | 0.01 | −0.18 | −0.25 | −0.13 |
| G-CSF | 0.10 | 0.16 | −0.09 | 0.15 | 0.67 ** | −0.01 | 0.46 * |
| Granzyme B | −0.06 | 0.48 * | 0.31 | 0.23 | 0.38 | 0.25 | 0.23 |
| TRAIL | 0.12 | −0.07 | 0.13 | 0.14 | 0.38 | 0.01 | 0.34 |
| EGF | 0.32 | 0.19 | 0.32 | −0.04 | 0.12 | −0.00 | 0.23 |
| PDGF-AA | −0.21 | 0.24 | −0.36 | −0.12 | 0.14 | 0.09 | −0.04 |
| PDGF-AB/BB | −0.28 | 0.25 | −0.09 | 0.00 | 0.42 | 0.07 | 0.09 |
| TGF-α | 0.13 | 0.34 | 0.02 | 0.18 | 0.48 * | 0.15 | 0.14 |
| VEGF | −0.21 | −0.01 | −0.18 | 0.03 | 0.24 | 0.03 | 0.05 |
| FGF β | −0.36 | −0.02 | 0.02 | 0.17 | 0.01 | −0.14 | −0.15 |
Pearson correlation analysis evaluated possible links between aqueous inflammatory factors and visual acuity, and OCTA parameters. *p < 0.05; **p < 0.01. Bold indicating p value was statistically significant. CRT, central retinal thickness; FAZ, foveal avascular zone; PERIM, perimeter of fovea; ILM-IPL, inner limiting membrane-inner plexiform layer; SVD, superficial vessel density; and DVD, deep vessel density.