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. 2023 Mar 9;9(5):459–473. doi: 10.1093/ehjqcco/qcad018

Figure 3.

Figure 3

Parameter estimates of age, period, and cohort effects on CAVD mortality by SDI quintiles. (A) Age effects are represented by the fitted longitudinal age curves of CAVD mortality (per 100 000 person-years) and the corresponding 95% CIs. (B) Period effects are represented by the relative risk of mortality of each period compared with the reference (period 1990–1994) adjusted for age and nonlinear cohort effects and the corresponding 95% CI. (C) Cohort effects are represented by the relative risk of mortality of each cohort compared with the reference (cohort 1921–1929) adjusted for age and nonlinear period effects and the corresponding 95% CI. Age, period, and cohort effects are stratified by sex. CAVD, calcific aortic valve disease; SDI, socio-demographic index; CI, confidence interval.