Table 9.
Summary of laboratory test values.
Test parameter (unit) | Time of testing | Statistics |
|||||
---|---|---|---|---|---|---|---|
Number of subjects | Mean | Standard deviation | Minimum | Median | Maximum | ||
White blood cell count (109/L) | Visit 1 | 23 | 10.380 | 3.091 | 6.40 | 9.500 | 18.60 |
Visit 5 | 5 | 11.320 | 1.264 | 9.60 | 11.200 | 13.10 | |
30 days after the last dose | 21 | 11.254 | 2.747 | 6.40 | 10.930 | 16.40 | |
Red blood cell count (1012/L) | Visit 1 | 23 | 4.676 | 0.533 | 3.65 | 4.570 | 5.89 |
Visit 5 | 5 | 4.822 | 0.230 | 4.50 | 4.840 | 5.11 | |
30 days after the last dose | 21 | 4.890 | 0.365 | 4.16 | 4.890 | 5.60 | |
Hemoglobin (g/L) | Visit 1 | 23 | 122.8 | 9.7 | 103 | 122.0 | 146 |
Visit 5 | 5 | 122.2 | 7.0 | 114 | 121.0 | 133 | |
30 days after the last dose | 21 | 127.1 | 11.7 | 110 | 127.0 | 157 | |
Hematocrit (%) | Visit 1 | 23 | 36.70 | 3.20 | 31.9 | 36.20 | 44.2 |
Visit 5 | 5 | 37.90 | 2.07 | 36.1 | 37.00 | 41.1 | |
30 days after the last dose | 21 | 38.37 | 3.37 | 32.0 | 37.80 | 45.8 | |
Platelet count (104/L) | Visit 1 | 23 | 43.85 | 12.09 | 29.3 | 39.20 | 76.1 |
Visit 5 | 5 | 50.88 | 9.20 | 40.2 | 53.60 | 59.6 | |
30 days after the last dose | 21 | 37.74 | 11.39 | 20.7 | 34.40 | 70.6 | |
Differential leukocyte count: | Visit 1 | 22 | 25.60 | 10.62 | 10.0 | 26.35 | 51.0 |
Neutrophils (%) | Visit 5 | 5 | 24.18 | 6.94 | 16.0 | 26.00 | 33.0 |
30 days after the last dose | 21 | 27.69 | 9.97 | 11.5 | 28.00 | 49.0 | |
Differential leukocyte count: | Visit 1 | 22 | 3.10 | 1.81 | 0.0 | 2.90 | 7.0 |
Eosinophils (%) | Visit 5 | 4 | 3.50 | 2.74 | 0.5 | 3.25 | 7.0 |
30 days after the last dose | 21 | 3.46 | 2.96 | 0.0 | 3.00 | 10.5 | |
Differential leukocyte count: | Visit 1 | 21 | 0.55 | 0.60 | 0.0 | 0.40 | 2.0 |
Basophils (%) | Visit 5 | 2 | 0.55 | 0.07 | 0.5 | 0.55 | 0.6 |
30 days after the last dose | 18 | 0.50 | 0.41 | 0.0 | 0.50 | 1.0 | |
Differential leukocyte count: | Visit 1 | 22 | 65.00 | 11.79 | 42.5 | 65.90 | 87.0 |
Lymphocytes (%) | Visit 5 | 5 | 66.22 | 6.46 | 60.0 | 65.00 | 77.0 |
30 days after the last dose | 21 | 63.96 | 9.93 | 44.0 | 63.00 | 85.0 | |
Differential leukocyte count: | Visit 1 | 22 | 4.47 | 3.17 | 1.0 | 3.15 | 10.5 |
Monocytes (%) | Visit 5 | 5 | 5.50 | 2.12 | 4.0 | 4.50 | 9.0 |
30 days after the last dose | 21 | 3.99 | 2.12 | 0.0 | 3.50 | 7.9 | |
Total bilirubin (mg/dL) | Visit 1 | 23 | 0.462 | 0.548 | 0.10 | 0.400 | 2.90 |
Visit 5 | 5 | 0.272 | 0.037 | 0.21 | 0.280 | 0.30 | |
30 days after the last dose | 22 | 0.324 | 0.130 | 0.10 | 0.300 | 0.60 |