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. 2023 Aug 7;21:531. doi: 10.1186/s12967-023-04322-0

Table 4.

lipid parameters including TG, TC, LDL-c, HDL-c, HDL-c/LDL-c ratio, and RC in relation to gestational diabetes mellitus

Exposure Non-GDM (n = 553) GDM (n = 37) Odds ratio (95% CI) P value
TC (mg/dL) 172.32 ± 26.97 180.89 ± 29.61  + 5 mg/dL: 1.035 (0.967, 1.107) 0.322
HDL-c(mg/dL) 65.29 ± 13.25 59.29 ± 16.45  + 5 mg/dL: 0.880 (0.753, 1.028) 0.107
LDL-c(mg/dL) 84.01 ± 21.29 84.29 ± 28.38  + 5 mg/dL: 0.990 (0.913, 1.073) 0.802
TG (mg/dL) 115.16 ± 41.67 176.22 ± 81.93  + 5 mg/dL:1.068 (1.027, 1.111)  < 0.001
HDL-c/LDL-c ratio 0.84 ± 0.31 0.81 ± 0.40 1 unit: 0.985 (0.287, 3.377) 0.980
RC (mg/dL) 23.025 ± 8.337 37.305 ± 18.628  + 5 mg/dL:1.458 (1.221, 1.741)  < 0.001
RC tertile
 T1 (< 18.50 mg/dL) 192 (34.72%) 2 (5.41%) Ref
 T2 (18.50–25.60 mg/dL) 190 (34.36%) 6 (16.22%) 1.404 (0.254, 7.771) 0.698
 T3 (≥ 25.60 mg/dL) 171 (30.92%) 29 (78.38%) 4.500 (0.973, 20.811) 0.054
 P for trend 0.011

Values are mean ± SD or n (%) unless otherwise indicated. Odds ratios (OR) were estimated by multivariate-logistic regression models adjusted for age, pre-pregnancy BMI, hepatic steatosis, AST, GGT, ALT, FPG, adiponectin, and insulin

CI confidence interval, Ref Reference, RC remnant cholesterol