Table 1.

Eligible Population and Effectiveness Assumptions for Minimum and Maximum Scenarios

Cancer Type	Minimum Scenario			Maximum Scenario
	1st Year USPSTF Recommendation	Eligible Population	Life-Years Gained per Screened Individual	1st Year USPSTF Recommendation	Eligible Population	Life-Years Gained per Screened Individual
Breast	1996	Women; age 50–69 y	0.029 [22]	1996	Women, age 40 + y	0.044 [22]
Colorectal	1996	Age 50–75 y	Flex sig + FITa: 0.009 [23]	2002	Age 45–75 y	Colonoscopy: 0.022 [23]
Cervical	1996	Women; age 21–65 y	PAPb: 0.089 [24]	1996	Women; age 21–65 y	21–30 PAP; 30–65 cotestingc: 0.096 [24]
Lung	2014	Current smoker or former smoker; age 50–80 y	0.0316 [25]	Limited benefit evidence, same as minimum scenario

^aFlex sig: flexible sigmoidoscopy, an endoscopic procedure that allows physician to examine the rectum and lower colon

^bPAP: a Pap smear or Pap test is a screening test for cervical cancer

^cCotesting: combination of PAP and human papilloma virus testing

FIT, fecal immunochemical test; USPSTF, US Preventive Services Task Force