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Financial commitment to unfunded salary and start-up
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If hiring Ph.D.s only on nontenure track, turnover is likely to be high
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Need to hire more research administrative staff to cover added grant submissions
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Need to obtain wet lab space (or dry lab for computational researchers) and pay institutional taxes on that space
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Ph.D.s do not generate clinical revenue
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Recruitment of top Ph.D. talent to basic science unit can be frustrating when basic science department offers are more attractive than clinical units leading to negative sentiment
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Leadership may be unfamiliar with how to structure career development or promotion packages for Ph.D. faculty
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Faculty meetings may rarely focus on topics of relevance to basic research or education
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Clinical chiefs, directors, and chairs may be less familiar with professional development needs for promotion and tenure for basic scientists
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Lack of access to Ph.D. and M.S. students without a joint appointment to a basic science unit or degree program
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Sense of isolation
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Staff in clinical unit may be less familiar with research grant submission and administration
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Fewer leadership opportunities and tenure track options may be limited
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Start-up packages and space norms may differ from basic science department at same academic medical center
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