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Failure to recover EBNA-1-deficient EBV in immortalized B cells
| Type of cells infected | Recombining plasmid | No. of clones with G418-resistant EBV carrying:
|
|
|---|---|---|---|
| Mutant EBNA-1 | Wild-type EBNA-1 | ||
| Raji | p652InNco | 11 | 2 |
| B95-8/CR2 | p652InNco | 4 | 1 |
| Human B cells | p652dl7 | 2 | 1 |
| Total | 17 | 4 | |
| Human B cells | p652InNco | 0 | 4 (P = 0.007)a |
Fisher exact test for consistency in a two-by-two table, comparing distributions of 17:4 and 0:4.
