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The promoter-proximal part of the LRS. The double-stranded DNA sequence is of B95-8 EBV DNA origin. The scale refers to the distance in base pairs from the transcription initiation site (+1). Transcription factor binding sites identified in a database search and possibly involved in the regulation of the LMP1 promoter are underlined. Two sets of mutations introduced in the LRS for a functional analysis of the E-box region are indicated below the sequence.
