Table 2.
Ovarian stimulation characteristics among the four groups.
| GROUP | Group 1 | Group 2 | Group 3 | Group 4 | P |
|---|---|---|---|---|---|
| No. of cases | 385 | 180 | 165 | 510 | |
| Protocol (%) | 0.190 | ||||
| GnRH agonist protocol | 83.64 (322/385) | 85.56 (154/180) | 86.67 (143/165) | 88.63 (452/510) | |
| GnRH antagonist protocol | 16.36 (63/385) | 14.44 (26/180) | 13.33 (22/165) | 11.37 (58/510) | |
| No. of basal antral follicles | 22.77 ± 4.15 | 23.18 ± 3.64 | 22.48 ± 4.61 | 23.50 ± 3.99ac | 0.010 |
| Starting dosage of Gn (IU) | 121.04 ± 27.62 | 123.12 ± 25.19 | 135.45 ± 28.73ab | 144.44 ± 34.65abc | <0.001 |
| Total dosage of Gn (IU) | 1631.67 ± 692.83 | 1696.81 ± 761.10 | 2245.70 ± 1060.56ab | 2644.74 ± 1163.04abc | <0.001 |
| Duration of Gn (d) | 10.98 ± 2.68 | 10.95 ± 2.74 | 12.29 ± 3.32ab | 13.04 ± 3.49ab | <0.001 |
| No. of oocytes retrieved | 14.87 ± 7.80 | 14.89 ± 8.61 | 13.30 ± 7.33 | 12.85 ± 7.21ab | <0.001 |
| No. of mature oocytes | 12.68 ± 6.90 | 12.72 ± 7.43 | 11.25 ± 6.62 | 11.08 ± 6.46a | <0.001 |
| No. of normal fertilization oocytes | 9.08 ± 5.60 | 9.04 ± 6.01 | 7.72 ± 4.63a | 7.83 ± 5.15a | <0.001 |
| No. of normal cleavage embryos | 8.84 ± 5.49 | 8.80 ± 5.87 | 7.50 ± 4.52a | 7.58 ± 5.08a | <0.001 |
| No. of available embryos | 7.47 ± 4.97 | 7.57 ± 5.50 | 6.89 ± 4.43 | 6.85 ± 4.77 | 0.219 |
| No. of good embryos | 3.04 ± 3.56 | 3.46 ± 3.94 | 2.99 ± 3.23 | 3.08 ± 3.58 | 0.633 |
| Blastocyst formation rate(%) | 69.98 (1902/2718) | 70.99 (893/1258) | 68.00 (622/916) | 71.98 (2168/3012) | 0.087 |
2 a: Significantly different to Group 1 b: Significantly different to Group 2 c: Significantly different to Group 3.