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. 2023 Jul 24;14:1202342. doi: 10.3389/fmicb.2023.1202342

Table 2.

Demographic and clinical characteristics of participating subjects (n = 275).

Variable Type of patient Value of p
Total Co-infected HIV/HBV HIV positive
n = 275 (100%) n = 32 (11.6%) n = 243 (88.4%)
Gender
Male 179 (65.1%) 21 (65.6%) 158 (65%) 1.0a
Age (median years-IQR)
38 (30–44) 37 (31–42) 38 (29–44) 0.73b
Risk factor
Heterosexual 182 (66.2%) 22 (68.8%) 160 (65.8%) 0.52a
Homosexual 24 (15.6%) 8 (25%) 35 (14.4%)
Bisexual 8 (5.8%) 2 (6.2%) 14 (5.8%)
ND 31 (12.4%) 0 (0%) 34 (14.0%)
CDC HIV classification
A 83 (30.2%) 10 (31.3%) 73 (30.0%) 0.62a
B 95 (34.5%) 13 (40.6%) 82 (33.7%)
C 89 (32.4%) 9 (28.1%) 80 (32.9%)
ND 8 (2.9%) 0 (0%) 8 (3.3%)
CD4+ count (cells/mm3)
Median - IQR 342 (200–532) 316 (183–447) 347 (203–532)
<200 68 (24.7%) 9 (28.1%) 59 (24.3%) 0.70a
200–500 128 (46.6%) 16 (50%) 112 (46.1%)
>500 79 (28.7%) 7 (21.9%) 72 (29.6%)
HIV viral load (copies/mL)
Median-IQR 84 (40–8,615) 702.5 (40–32188.8) 80 (40–7220.5)
Undetectable ≤50 119 (43.2%) 12 (37.5%) 107 (44.0%) 0.20a
Low 51–10,000 94 (34.2%) 9 (28.1%) 85 (35.0%)
Mid 10,001-99,999 42 (15.3%) 9 (28.1%) 33 (13.6%)
High >100,000 20 (7.3%) 2 (6.3%) 18 (7.4%)
HBV serologic markers
HBsAg
Negative 266 (96.7%) 23 (71.9%) 243 (100%) <0.05a,*
Positive 9 (3.3%) 9 (28.1%) 0 (0%)
Anti-HBc
Negative 206 (74.9%) 19 (59.4%) 187 (77%) 0.05a,*
Positive 69 (25.1%) 13 (40.6%) 56 (23%)
Anti-HBs
Negative 168 (61.1%) 22 (68.7%) 146 (60.1%) 0.45a
Positive 107 (38.9%) 10 (31.3%) 97 (39.9%)
HBV vaccination
No 54 (19.6%) 8 (25%) 46 (18.9%) 0.29a
Yes 47 (17.1%) 3 (9.4%) 44 (18.1%)
ND 174 (63.3%) 21 (65.6%) 153 (63.0%)

ND, No data; HBsAg, hepatitis B surface antigen; Anti-HBc, hepatitis B core antibody; Anti-HBs, hepatitis B surface antibody; CDC, Center for Disease Control and Prevention; IQR, interquartile range. aChi square test; bMann–Whitney test. *Statistical differences were observed.