Table 2.

Evaluations of CRP and CDAI before and after optimization in the two cohorts.

Variables	Patients with q8w/q4w SC (n = 105)		Patients with IV reinduction (n = 23)		P value
	median (IQR)	Time to assessment [weeks, median (range)]	median (IQR)	Time to assessment [weeks, median (range)]
CRP delta variation	0.4 (−0.6, 7.2)	8.0 (8.0, 16.0)	3.2(−0.8, 8.4)	8.0 (8.0, 8.0)	0.225
CDAI delta variation	17.0 (−4.4, 65.9)	8.0 (8.0, 16.0)	69.0 (10.7, 151.0)	8.0 (8.0, 16.0)	0.013

IQR, interquartile range; q8/4w, every 8/4 weeks; SC, subcutaneous; IV, intravenous; CRP, C-reactive protein; CDAI, Crohn’s disease activity index; CRP delta variation: deviation of CRP between pre-and post-treatment; CDAI delta variation: deviation of CDAI between pre-and post-treatment.