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. 2022 Jul 22;1:903531. doi: 10.3389/fnimg.2022.903531

Figure 1.

Figure 1

Eight hundred and eight-nanometer laser promoted neuronal activity, and 1,064-nm laser promoted microglial fAβ phagocytosis. (A) Confocal fluorescence colocalization imaging for microglia to phagocytosed fAβ after 808-, 1,064-, 1,210-, and 1,470-nm laser PBM treatment; scale bar, 50 μm; (B) the quantification of the fluorescence measurements of (A), n = 20; (C) flow cytometry for fAβ phagocytosis amount by microglia irradiated with the 808-, 1,064-, 1,210-, and 1,470-nm lasers at six different doses, respectively; (D) CCK-8 viability assay of SH-SY5Y neuroblastoma cells, n = 8. Data in (B) and (D) are mean ± SEM of at least three independent experiments, *p < 0.05, **p < 0.001, and ***p < 0.0001.