Table 2.
Univariable Cox regression analyses for outcomes in critically ill patients with AMI.
| Variable | 30-day mortality | 90-day mortality | ||
|---|---|---|---|---|
| HR (95%CI) | p-value | HR (95%CI) | p-value | |
| Demographics | ||||
| Age (year) | 1.04 (1.03,1.04) | <0.001 | 1.04 (1.03,1.05) | <0.001 |
| Male gender | 0.7 (0.61,0.82) | <0.001 | 0.72 (0.63,0.83) | <0.001 |
| Ethnicity (ref. = White) | ||||
| Black | 0.75 (0.56,1.01) | 0.062 | 0.67 (0.52,0.88) | 0.004 |
| Other | 1.22 (1.03,1.44) | 0.022 | 1.15 (0.99,1.34) | 0.059 |
| Vital signs | ||||
| SBP (mmHg) | 0.97 (0.96,0.97) | <0.001 | 0.97 (0.96,0.97) | <0.001 |
| DBP (mmHg) | 0.98 (0.97,0.99) | <0.001 | 0.98 (0.97,0.99) | <0.001 |
| MBP (mmHg) | 0.96 (0.95,0.97) | <0.001 | 0.96 (0.96,0.97) | <0.001 |
| HR (beats/min) | 1.02 (1.02,1.03) | <0.001 | 1.02 (1.01,1.02) | <0.001 |
| RR (beats/min) | 1.17 (1.15,1.19) | <0.001 | 1.15 (1.13,1.17) | <0.001 |
| Temperature (°C) | 0.58 (0.53,0.65) | <0.001 | 0.63 (0.57,0.7) | <0.001 |
| SpO2 (%) | 0.88 (0.87,0.9) | <0.001 | 0.89 (0.88,0.9) | <0.001 |
| Comorbidities, | ||||
| Congestive heart failure | 1.52 (1.31,1.77) | <0.001 | 1.59 (1.39,1.82) | <0.001 |
| Peripheral vascular disease | 1.3 (1.07,1.58) | 0.007 | 1.39 (1.18,1.64) | <0.001 |
| Cerebrovascular disease | 1.7 (1.41,2.06) | <0.001 | 1.69 (1.43,2) | <0.001 |
| Chronic pulmonary disease | 1.24 (1.06,1.46) | 0.009 | 1.29 (1.11,1.48) | <0.001 |
| Rheumatic disease | 1.0,083 (0.6861,1.4817) | 0.966 | 1.0071 (0.7182,1.4122) | 0.967 |
| Diabetes | 0.92 (0.79,1.08) | 0.303 | 0.94 (0.82,1.07) | 0.357 |
| Paraplegia | 1.75 (1.22,2.51) | 0.002 | 1.7 (1.23,2.35) | 0.001 |
| Renal disease | 1.36 (1.16,1.58) | <0.001 | 1.41 (1.23,1.62) | <0.001 |
| Malignant cancer | 2.06 (1.67,2.55) | <0.001 | 2.42 (2.02,2.89) | <0.001 |
| Severe liver disease | 2.16 (1.49,3.14) | <0.001 | 1.94 (1.37,2.75) | <0.001 |
| Hypercholesterolemia | 0.89 (0.64,1.24) | 0.497 | 0.82 (0.61,1.1) | 0.19 |
| Ventricular tachycardia | 2.04 (1.62,2.58) | <0.001 | 2.04 (1.66,2.51) | <0.001 |
| Hypertension | 0.6 (0.51,0.71) | <0.001 | 0.6 (0.52,0.69) | <0.001 |
| Laboratory tests | ||||
| Hemoglobin (g/dl) | 0.91 (0.88,0.95) | <0.001 | 0.89 (0.86,0.92) | <0.001 |
| Platelet (109/L) | 1.0001 (0.9993,1.0008) | 0.887 | 1.0002 (0.9995,1.0008) | 0.642 |
| WBC (109/L) | 1.0099 (1.007,1.0129) | <0.001 | 1.0092 (1.0064,1.0121) | <0.001 |
| Glucose (mg/dl) | 1 (1,1.0001) | 0.128 | 1 (1,1.0001) | 0.13 |
| Calcium (mmol/L) | 0.68 (0.61,0.75) | <0.001 | 0.71 (0.65,0.78) | <0.001 |
| Chloride (mmol/L) | 0.98 (0.97,0.99) | 0.002 | 0.98 (0.97,0.99) | 0.001 |
| Creatinine (mg/dl) | 1.09 (1.06,1.11) | <0.001 | 1.08 (1.05,1.1) | <0.001 |
| Sodium (mmol/L) | 1.03 (1.02,1.05) | <0.001 | 1.03 (1.01,1.05) | <0.001 |
| PTT (sec) | 1.01 (1.01,1.01) | <0.001 | 1.01 (1.01,1.02) | <0.001 |
| Drug use | ||||
| Warfarin | 0.33 (0.22,0.48) | <0.001 | 0.44 (0.33,0.58) | <0.001 |
| Aspirin | 0.65 (0.56,0.76) | <0.001 | 0.67 (0.59,0.77) | <0.001 |
| Beta-blockers | 0.65 (0.5,0.84) | 0.001 | 0.7 (0.56,0.87) | 0.002 |
AMI, acute myocardial infarction; SBP, systolic blood pressure; DBP, diastolic blood pressure; MBP, mean blood pressure; HR, heart rate; RR, respiratory rate; SpO2, percutaneous oxygen saturation; WBC, white blood cell; Chronic pulmonary disease, chronic obstructive pulmonary disease; PTT, partial thromboplastin time.