Table 7.

Overview of axial diffusivity differences in cannabis users compared to controls, and their association with cannabis exposure levels and other variables.

References	Cannabis users vs. controls	Correlations
Cousijn et al. (2022)	n.s.	n.s. onset age, duration, grams/past 2 wks, dependence severity
Lichenstein et al. (2022)	n.s. anterior thalamic radiations, cingulum	-
Sweigert et al. (2020)	n.s. inferior, superior, and middle cerebellar peduncles, pontine crossing tract	Neg. cor craving scores (MCQ-SF) and middle cerebellar peduncle n.s. CUDIT-R total score
Levar et al. (2018)	n.s. uncinate fasciculus	-
Jakabek et al. (2016)	n.s.	Pos. cor. duration and cingulate gyrus. Neg. cor. onset age and cingulate gyrus. n.s. frequency of current use
Orr et al. (2016)	n.s.	-
Rigucci et al. (2016)	↑ corpus callosum	Subgroup analyses: corpus callosum in daily users > occasional users > controls in corpus callosum in daily and high potency users > low potency users > controls and weekly users trend corpus callosum in age onset < 15 years vs. >15 year
Filbey et al. (2014)	n.s.	-
Zalesky et al. (2012)	n.s.	Pos. cor. onset age and commissural fibre, fimbria
Ashtari et al. (2009)	↓ superior temporal gyrus tracts and internal capsule [voxel wise analysis of covariance] ↓ motor tracts [tractography]	n.s. onset age, duration, dosage, abstinence length

Cor, correlated; n.s., non-significant; Neg, negative; Pos, positive; wks, weeks; ↓, Cannabis Users < Controls; ↑ Cannabis Users > Controls.