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. 2023 Jul 24;14:1198970. doi: 10.3389/fphar.2023.1198970

TABLE 1.

Extraction of chemical compounds from Summer Savory.

Part of summer savory Extraction method Bioactive compounds Solvent Reference
Oil (Ariel part) Conventional Carvacrol, a-pinene, p-cymene, c-terpinene, and thymol methyl ether Water/steam Silva et al. (2005), Skočibušić et al. (2006)
Leaves, flower buds, and calyx UV-visible spectrophotometry Flavonoids Ethanol Khlebnikova et al. (2022)
Ariel part Mass spectrometer Rosmarinic acid, caffeic acid and naringenin acid Methanol Boroja et al. (2018)
Flowers, leaves, and steam Conventional Phenolic and flavonoids Ethanol Predescu et al. (2020)
Flowers Non-conventional Rutin and quercetin Ethanol Mašković et al. (2017)
Leaves Carvacrol and γ-terpinene Radácsi et al. (2016)
Seeds Conventional Carvacrol, c-terpinene, para-cymene; and the minor components a-terpinene, myrcene, camphene, and a-pinene Svoboda and Greenaway (2003)
GC and GCMS
Blooming and shade-dried plants HPTLC and HPLC Rosmarinic acid (RA), caffeic acid (CA), chlorogenic acid (ChA), apigenin, luteolin, catechin, quercetin, rutin, and hyperoside Methanol Shanaida et al. (2021)
Dried NMR Luteolin, apigenin, and quercetin Ethanol and acetone Exarchou et al. (2002)
Oil (flowers) GC-MC α-Phellandrene and myrcene Helium Stankov et al. (2022)
Oil GC-MC Limonene Helium Stankov et al. (2022)
Extract (Ariel parts) UHPLC/DAD/HESI-MS/MS hydroxycinnamic acids, caffeic and isoferulic acids Acetic acid with water Boroja et al. (2018)
Ariel parts UHPLC/DAD/HESI-MS/MS Flavonol (quercetin), flavonol glycosides (isoquercitrin, astragalin, quercitrin), and coumarin derivatives (aesculin and aesculetin) Acetic acid with water Boroja et al. (2018)
Dried HPLC-DAD Protocatechuic acid Water and formic acid Mašković et al. (2017)
Dried HPLC-DAD p-Hydroxybenzoic acid Water and formic acid Mašković et al. (2017)