Table 1.

Phasic responses of prelimbic neurons separated into classes based on epoch (pre- vs. post-lever press) and direction of response (excitation (↑), inhibition (↓), not significant (-))

Self-Admin		Significant: 110/259 (42.6%)
Pre	Post	Pre	Post	Pre	Post	Pre	Post
↑	↑	↑	↓	↑	-	-	↑
16 (6.2%)		2 (0.8%)		14 (5.4%)		28 (10.8%)
↓	↓	↓	↑	↓	-	-	↓
15 (5.8%)		3 (1.2%)		14 (5.4%)		18 (7.0%)
Early Ext		Significant: 65/283 (23.0%)
↑	↑	↑	↓	↑	-	-	↑
15 (5.3%)		0 (0%)		12 (4.2%)		13 (4.6%)
↓	↓	↓	↑	↓	-	-	↓
7 (2.5%)		0 (0%)		9 (3.2%)		9 (3.2%)
Late Ext		Significant: 24/162 (14.9%)
↑	↑	↑	↓	↑	-	-	↑
7 (4.3%)		0 (0%)		2 (1.2%)		2 (1.2%)
↓	↓	↓	↑	↓	-	-	↓
2 (1.2%)		0 (0%)		6 (3.7%)		5 (3.1%)
Cue Reinst		Significant: 98/255 (38.5%)
↑	↑	↑	↓	↑	-	-	↑
17 (6.7%)		2 (0.8%)		14 (5.5%)		24 (9.4%)
↓	↓	↓	↑	↓	-	-	↓
15 (5.9%)		1 (0.4%)		12 (4.7%)		13 (5.1%)
Coc Reinstat		Significant: 82/195 (42.2%)
↑	↑	↑	↓	↑	-	-	↑
14 (7.2%)		2 (1.0%)		15 (7.7%)		10 (5.1%)
↓	↓	↓	↑	↓	-	-	↓
11 (5.6%)		1 (0.5%)		16 (8.2%)		13 (6.7%)

For each stage of the study (self-administration, early and late extinction, and cue-induced and cocaine-induced reinstatement), neurons are separated into 8 categories based on whether or not they were significantly excited or inhibited in the 2-s epoch pre and/or post lever press