Table 1. Demographics of male patients with pancreatic cancer from chart review and serum sample cohorts.
| Covariate | Level | Chart review cohort (cohort A) (n=35) | Serum sample cohort (cohort B) (n=89) |
|---|---|---|---|
| Age at diagnosis (years) | Median (range) | 61.9 (22.7–87.5) | 66.0 (44.0–87.0) |
| Race | African American | 0 (0.0) | 3 (3.4) |
| White | 35 (100.0) | 85 (95.5) | |
| Unknown | 0 (0.0) | 1 (1.1) | |
| BMI at diagnosis (kg/m2) | Median (range) | 31.3 (13.7–59.7) | 27.8 (17.2–52.2) |
| Obese (BMI >30 kg/m2) | Yes | 20 (57.1) | 34 (38.2) |
| No | 15 (42.9) | 55 (61.8) | |
| Diabetes | Yes | 16 (45.7) | 38 (42.7) |
| No | 19 (54.3) | 51 (57.3) | |
| Heart disease | Yes | 18 (51.4) | 63 (70.8) |
| No | 17 (48.6) | 26 (29.2) | |
| Hypo/hyperthyroidism | Yes | 6 (17.1) | 10 (11.2) |
| No | 29 (82.9) | 79 (88.8) | |
| Obstructive sleep apnea | Yes | 4 (11.4) | 12 (13.5) |
| No | 31 (88.6) | 77 (86.5) | |
| HIV/AIDS | Yes | 0 (0.0) | 0 (0.0) |
| No | 35 (100.0) | 89 (100.0) | |
| Chronic kidney disease | Yes | 2 (5.7) | 3 (3.4) |
| No | 33 (94.3) | 86 (96.6) | |
| Sarcoidosis | Yes | 0 (0.0) | 0 (0.0) |
| No | 35 (100.0) | 89 (100.0) | |
| Corticosteroid use | Yes | 2 (5.7) | 5 (5.6) |
| No | 33 (94.3) | 84 (94.4) | |
| Opioid use | Yes | 5 (14.3) | 25 (28.1) |
| No | 30 (85.7) | 64 (71.9) | |
| Pre-existing autoimmune disease | Yes | 1 (2.9) | 3 (3.4) |
| No | 34 (97.1) | 86 (96.6) | |
| Previous cancer diagnosis | Yes | 7 (20.0) | 22 (24.7) |
| No | 28 (80.0) | 67 (75.3) | |
| Clinical stage | I | 8 (22.9) | 17 (19.1) |
| II | 7 (20.0) | 38 (42.7) | |
| III | 2 (5.7) | 13 (14.6) | |
| IV | 17 (48.6) | 21 (23.6) | |
| Not staged | 1 (2.9) | 0 (0.0) | |
| Histology | Adenocarcinoma | 18 (51.4) | 89 (100.0) |
| Neuroendocrine tumor | 17 (48.6) | 0 (0.0) | |
| Testosterone level (ng/dL) | Median (range) | 365 (5–1,497) | 301 (123–2,378) |
| Low testosterone (<300 ng/dL) | Yes | 20 (57.1) | 44 (49.4) |
| No | 15 (42.9) | 45 (50.6) | |
| Prior testosterone assessment | Yes | – | 2 (2.2) |
| No | – | 87 (97.8) | |
| Symptoms of low testosterone | Yes | – | 62 (69.7) |
| No | – | 27 (30.3) |
Except where otherwise noted, data are presented as n (%). BMI, body mass index; HIV/AIDS, human immunodeficiency virus or acquired immunodeficiency syndrome.