Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2023 Jun 26;20(8):1213–1221. doi: 10.1038/s41592-023-01914-y

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© The Author(s), under exclusive licence to Springer Nature America, Inc. 2023

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

PMC Copyright notice

Fig. 3 — a, The principal bundle decomposition and annotated HLA class II genes in each of the haplotype sequences. The auxiliary tracks below each sequence on the left panel show the locations of the genes. The colors of the auxiliary tracks match the gene list of genes identified for each haplotype on the right. b, The MAP-graph generated by PGR-TK. c, PCA plots of the MHC class II sequences. Each panel highlights the different gene haplotype combinations. The vertical color bars indicate the matched haplotype groups in b and c. The circled symbols indicate the haplotypes belong to the corresponding group. The dotted lines represent the connection between the two haplotypes of individuals included in the analysis set who possess both haplotypes. The population groups, African Ancestry(AFR), American Ancestry (AMR), South Asia Ancestry(SAS), East Asia Ancestry(EAS) and not applicable (NA), are indicated with different markers of different colors.