Table 1. Baseline characteristics of patients.
Parameters | low DAPT score (score <2, n= 1,646) | high DAPT score (score ≥ 2, n= 485) | P Value |
---|---|---|---|
Age, years | 71.0±4.6 | 69.8±3.9 | <0.001*** |
Female | 671 (40.8) | 113 (23.3) | <0.001*** |
BMI, kg/m2 | 25.3±3.1 | 25.1±3.2 | 0.381 |
Hypertension | 1,165 (70.8) | 341 (70.3) | 0.842 |
Peripheral vascular disease | 51 (3.1) | 30 (6.2) | 0.002*** |
Previous stroke | 250 (15.2) | 96 (19.8) | 0.016*** |
Prior CABG | 77 (4.7) | 51 (10.5) | <0.001*** |
ACS | 983 (59.7) | 309 (63.7) | 0.114 |
Ccr <60 ml/min | 355 (21.6) | 105 (21.6) | 0.969 |
SYNTAX score | 11.9±8.5 | 13.3±9.0 | 0.002*** |
Factors in DAPT score | |||
Age ≥ 75 | 411 (25.0) | 46 (9.5) | <0.001*** |
Cigarette smoking | 564 (34.3) | 352 (72.6) | <0.001*** |
Diabetes | 374 (22.7) | 291 (60.0) | <0.001*** |
Prior PCI or MI | 411 (25.0) | 331 (68.2) | <0.001*** |
MI at presentation | 152 (9.2) | 150 (30.9) | <0.001*** |
CHF or LVEF <30% | 3 (0.2) | 49 (10.1) | <0.001*** |
Stent diameter <3mm | 801 (48.7) | 398 (82.1) | <0.001*** |
Vein graft stent | 0 (0) | 7 (1.4) | <0.001*** |
Paclitaxel-eluting stent | 21 (1.3) | 25 (5.2) | <0.001*** |
2nd or 3rd generation stent | 1,254 (76.2) | 333 (68.7) | <0.001*** |
Values are presented as mean±standard deviation, or n (%).
DAPT, dual-antiplatelet therapy; BMI, body mass index; MI, myocardial infarction; PCI, percutaneous coronary intervention; CABG, coronary artery bypass grafting; ACS, acute coronary syndrome; Ccr, creatinine clearance rate; SYNTAX, Synergy between Percutaneous Coronary Intervention with Taxus and Cardiac Surgery; CHF, congestive heart failure; LVEF, left ventricular ejection fraction
***P values indicating statistical significance