Table 3.
Patient Characteristics by PBC-40 Itch Severity
| = 0 No itch | > = 1 to < 7 Mild itch | > = 7 Clinically significant itch | P-value† | |
|---|---|---|---|---|
| All Patients, n (%) | 41 (19) | 107 (51) | 63 (30) | 0.844 |
| Gender Female, n (%) | 38 (93) | 97 (91) | 59 (94) | |
| Current age (years) | ||||
| Median (Q1–Q3) | 64 (56–71) | 64 (55–71) | 58 (52–64) | 0.0124 |
| Age at diagnosis (years) | ||||
| Median (Q1–Q3) | 52 (42–59) | 54 (46–60) | 49 (39–56) | 0.0398 |
| Most recent ALP (IU/L) | ||||
| Median (Q1–Q3) | 153 (126–228) | 143 (116–187) | 177 (133–284) | 0.0019 |
| Most recent total bilirubin (mg/dl) | ||||
| Median (Q1-Q3) | 0.5 (0.4–0.8) | 0.6 (0.4–0.8) | 0.8 (0.5 – 1.2) | 0.0007 |
| Cirrhosis n (%) | 15 (37) | 29 (27) | 30 (48) | 0.0277 |
| Decompensated Cirrhosis | ||||
| N | 15 | 29 | 30 | |
| Yes, n (%) | 5 (33) | 7 (24) | 18 (60) | 0.0174 |
ALP Alkaline phosphatase
†P values are tests for any difference between the three groups (CS itch, mild itch, and no itch)