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. 2022 Oct 27;24(7):1121–1139. doi: 10.1007/s10198-022-01538-7

Table 2.

Participant characteristics based on lung function tests

All Participants PFT Incomplete/No PFT p
(n = 162) (n = 112) (n = 50)
Age 0.8
 Mean (SD) 73.8 (7.6) 73.7 (7.4) 74.1 (8.2)
 Median [IQR] 74.0 [69–78] 74.0 [69–78] 74.0 [69–78]
Age group, n (%) 0.9
 < 65 19 (11.7) 13 (11.6) 6 (12.0)
 65–75 82 (50.6) 56 (50.0) 26 (52.0)
 75–85 48 (29.6) 35 (31.3) 13 (26.0)
 > 85 13 (8.0) 8 (7.1) 5 (10.0)
Gender, n (%) 0.7
 Male 99 (61.1) 70 (62.5) 29 (58.0)
 Female 63 (38.9) 42 (37.5) 21 (42.0)
Race, n (%) 0.4
 Caucasian 145 (89.5) 100 (89.3) 45 (90.0)
 Other 9 (5.6) 8 (7.1) 1 (2.0)
 Missing 8 (4.9) 4 (3.6) 4 (8.0)
Marital Status, n (%) 0.04
 Married/De facto/Partner 115 (71.0) 85 (75.9) 30 (60.0)
 Divorced/Widowed/Separated/Single 45 (27.8) 25 (22.3) 20 (40.0)
 Missing 2 (1.2) 2 (1.8) 0 (0.0)
State of usual residence, n (%)  < 0.001
 NSW 66 (40.7) 57 (50.9) 9 (18.0)
 VIC 31 (19.1) 21 (18.8) 10 (20.0)
 QLD 14 (8.6) 5 (4.5) 9 (18.0)
 SA 25 (15.4) 22 (19.6) 3 (6.0)
 TAS 16 (9.9) 5 (4.5) 11 (22.0)
WA 6 (3.7) 0 (0.0) 6 (12.0)
 ACT 2 (1.2) 2 (1.8) 0 (0.0)
 NT 2 (1.2) 0 (0.0) 2 (4.0)
Remoteness area, n (%) 0.1
 Major city 99 (61.1) 75 (67.0) 24 (48.0)
 Inner regional 43 (26.5) 28 (25.0) 15 (30.0)
 Outer regional/ Remote 16 (9.9) 8 (7.1) 8 (16.0)
 Missing 4 (2.5) 1 (0.9) 3 (6.0)
Employment, n (%) 0.9
 Full time/Part time/Unpaid work 19 (11.7) 14 (12.5) 5 (10.0)
 Retired 135 (83.3) 92 (82.1) 43 (86.0)
 Unemployed 7 (4.3) 5 (4.5) 2 (4.0)
 Missing 1 (0.6) 1 (0.9) 0 (0.0)
Income ($), n (%) 0.2
 < 400/week 56 (34.6) 39 (34.8) 17 (34.0)
 400–799/week 50 (30.9) 33 (29.5) 17 (34.0)
 800–1249/week 15 (9.3) 8 (7.1) 7 (14.0)
 > 1250/week 12 (7.4) 11 (9.8) 1 (2.0)
 Missing 29 (17.9) 21 (18.8) 8 (16.0)
Concession status, n (%)
 DVA 7 (4.3) 4 (3.6) 3 (6.0) 0.8
 Pensioner 107 (66.0) 71 (63.4) 36 (72.0) 0.4
 Seniors 39 (24.1) 20 (17.9) 19 (38.0) 0.01
 Other 24 (14.8) 14 (12.5) 10 (20.0) 0.3
 No card 30 (18.5) 25 (22.3) 5 (10.0) 0.1
Comorbidities, n (%) 1.0
 No 33 (20.4) 23 (20.5) 10 (20.0)
 Yes 129 (79.6) 89 (79.5) 40 (80.0)
BMI kg/m2 (n = 154) 0.1
 Mean ± SD 28.1 (4.8) 27.6 (4.3) 29.3 (5.8)
 Median [IQR] 28 [25–31] 27 [25–30] 28 [25–33]
 Missing 8 (4.9) 0 (0.0) 8 (16.0)
GAP stage, (n = 108)  < 0.001
 Stage I 46 (28.4) 46 (41.1) 0 (0)
 Stage II 52 (32.1) 52 (46.4) 0 (0)
 Stage III 10 (6.2) 10 (8.9) 0 (0)
 Not classified 54 (33.3) 4 (3.6) 50 (100)
FVC, (n = 112)  < 0.001
 > 75 82 (50.6) 82 (73.2) 0 (0.0)
 50–75 26 (16.0) 26 (23.2) 0 (0.0)
 < 50 4 (2.5) 4 (3.6) 0 (0.0)
 Not classified 50 (30.9) 0 (0.0) 50 (100.0)
CPI, (n = 108)  < 0.001
 < 40 38 (23.5) 38 (33.9) 0 (0.0)
 > 40 70 (43.2) 70 (62.5) 0 (0.0)
 Not classified 54 (33.3) 4 (3.6) 50 (100.0)
Medications, n (%)
 Antifibrotics 96 (59.3) 75 (67.0) 21 (42.0)  < 0.001
 Other medications for used IPF (limited evidence) 81 (50.0) 54 (48.2) 27 (54.0) 0.61
 Medications not recommended for IPF treatment 27 (16.7) 12 (10.7) 15 (30.0)  < 0.001

n number of participants, SD Standard deviation, $ Australian dollars, FVC forced vital capacity percent predicted, GAP Gender, Age, Physiology; CPI Composite Physiological Index. Not classified (includes participants with missing or incomplete PFTs), BMI Body Mass Index, IQR interquartile range, Antifibrotics medications include pirfenidone and nintedanib. Medications not recommended for IPF treatment include prednisolone, n-acetylcysteine, warfarin and azathioprine. Other medications used for IPF (limited evidence) includes anti-reflux drugs. NSW New South Wales, VIC Victoria, SA South Australia, QLD Queensland, TAS Tasmania, WA Western Australia, ACT Australian Capital Territory, NT Northern Territory

p value for appropriate test (t test or Chi-squared test). Bolded results represent statistically significant results (p < 0.05)