Table 2.
Bivariate and multivariate analysis of the possible predictors of perforation in patients with non-muscle-invasive bladder cancer (N = 1570)
| Parameters | Bivariate analysis | Multivariate regression | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Occurrence of bladder perforation | Odds ratio | p-value | Odds ratio | 95% CI | p-value | ||||
| No N: 1412 (%) |
Yes N: 158 (%) |
||||||||
| Gender | |||||||||
| Male | 1219 | (90) | 131 | (10) | 0.2 | ||||
| Female | 193 | (87) | 27 | (13) | |||||
| Previous TURBT | |||||||||
| No | 1073 | (92) | 89 | (8) | 13 | 0.001 | 2 | 1.4– | 0.001 |
| Yes | 339 | (83) | 69 | (17) | 2.8 | ||||
| Number of previous TURBT | |||||||||
| De novo | 1055 | (91) | 107 | (9) | |||||
| One recurrence | 205 | (87) | 31 | (13) | |||||
| Two recurrences | 88 | (84) | 6 | (16) | 19 | 0.001 | 0.08 | ||
| Three recurrences | 39 | (84) | 8 | (16) | |||||
| > Three recurrence | 25 | (81) | 6 | (19) | |||||
| Tumor number | |||||||||
| Single | 725 | (91) | 71 | (9) | 3.4 | 0.12 | 0.06 | ||
| Multiple | 687 | (88) | 87 | (12) | |||||
| Tumor size | |||||||||
| Less than 3 cm | 735 | (89) | 85 | (11) | |||||
| 3 cm or more | 677 | (90) | 73 | (10) | 0.7 | ||||
| Tumor grade | |||||||||
| Grade I | 170 | (91) | 18 | (9) | |||||
| Grade II | 754 | (91) | 78 | (9) | 0.6 | ||||
| Grade III | 488 | (89) | 62 | (11) | |||||
| Tumor stage | |||||||||
| Ta | 354 | (97) | 23 | (6) | |||||
| T1 | 956 | (90) | 127 | (11) | 7 | 0.045 | |||
| Primary CIS | 102 | (95) | 8 | (7) | |||||
| Tumor site (location) | |||||||||
| Posterior | 315 | (91) | 31 | (9) | 0.08 | ||||
| Lateral walls | 459 | (87) | 62 | (13) | |||||
| Anterior and domal | 123 | (86) | 20 | (14) | |||||
| Trigone and BN | 86 | (93) | 8 | (7) | |||||
| Multicentric | 429 | (92) | 37 | (8) | |||||
| Obturator jerk | |||||||||
| No | 1404 | (90) | 149 | (10) | 30 | 0.0001 | 10 | 3.8– | 0.0001 |
| Yes | 8 | (47) | 9 | (53) | 27.2 | ||||
Bold values indicate statistically significant values