FIG. 5.

Comparison of viral replication in the pancreatic tissues of BALB/cByJ mice and various immunologically deficient strains of mice. Groups of three to five mice were infected intraperitoneally with 10⁴ PFU of CB4-V. Pancreatic tissues were harvested at different times p.i. Homogenates of individual samples were assayed for viral infectivity by plaque assay. Mean values (and standard deviations) are shown. (A) BALB/cByJ and CD4 ko female mice; (B) BALB/cByJ and IL-4 ko female mice; (C) BALB/cByJ and IFN-γ ko female mice; (D) BALB/cByJ and CD4 ko male mice; (E) BALB/cByJ and IL-4 ko male mice; (F) BALB/cByJ and IFN-γ ko male mice.