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. 2023 Aug 7;13:12765. doi: 10.1038/s41598-023-39503-w

Table 3.

Cytokine analysis according to lenvatinib treatment.

Mean concentration of cytokines (pg/ml) P valuea P valueb
Pre-treatment (4 samples from 4 patients) On-treatment (23 samples from 10 patients) Off-treatment (4 samples from 4 patients)
IL-2 0.25 (0.27) 0.09 (0.11) 0.14 (0.05) 0.31 0.37
IL-10 8.08 (3.07) 8.34 (1.81) 7.24 (1.21) 0.88 0.18
IL-15 2.50 (0.44) 3.14 (1.21) 3.67 (0.83) 0.08 0.32
TGF-beta 141.00 (7.12) 135.61 (12.43) 139.00 (6.68) 0.26 0.45

Variables are presented as means (standard deviations).

aP values for the comparison between the pre-treatment (4 samples from 4 patients) and on-treatment (23 samples from 10 patients).

bP values for the comparison between the on-treatment (23 samples from 10 patients) and off-treatment (4 samples from 4 patients).