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. 2023 Jul 26;94:104729. doi: 10.1016/j.ebiom.2023.104729

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© 2023 The Author(s)

This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).

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Fig. 2 — Immunohistochemical analyses of peripheral blood mononuclear cells (PBMC) from PASC patients and SARS-CoV-2-infected participants fully recovered (Recov). Cytospins were prepared directly after isolation of PBMC. Absent IDO1 stain in PASC and Recov (A and B; a positive control was done separately: not shown). IDO2 stain in PASC and recover (C and D). IDO2-expressing cells are predominantly monocytes, CD4 lymphocytes and B lymphocytes (C, E–H). 3OH-anthranilic acid was shown in PBMC from PASC patients and not in those from healthy individuals (I, J). Nuclear localization of AHR in IDO2-expressing PBMC from PASC patients (K).

Fig. 2 — Immunohistochemical analyses of peripheral blood mononuclear cells (PBMC) from PASC patients and SARS-CoV-2-infected participants fully recovered (Recov). Cytospins were prepared directly after isolation of PBMC. Absent IDO1 stain in PASC and Recov (A and B; a positive control was done separately: not shown). IDO2 stain in PASC and recover (C and D). IDO2-expressing cells are predominantly monocytes, CD4 lymphocytes and B lymphocytes (C, E–H). 3OH-anthranilic acid was shown in PBMC from PASC patients and not in those from healthy individuals (I, J). Nuclear localization of AHR in IDO2-expressing PBMC from PASC patients (K).