Table 1.

Characteristics of study participants of whom EDTA plasma or serum was analyzed for kynurenine metabolites.

	PASC	Non-hospitalized Covid-19	Hospitalized Covid-19	p-value	Fatal/severe
	n = 15	n = 12	n = 15		n = 12
Age (median [IQR])	49.00 [42.50, 54.00]	51.00 [39.25, 60.00]	61.00 [54.50, 65.00]	0.004	67.50 [64.25, 74.25]
Gender = Male (%)	3 (20.0)	3 (25.0)	9 (60.0)	0.048	10 (83.3)
PCR positive (%)				<0.001
No	1 (6.7)	0 (0.0)	0 (0.0)		0 (0.0)
PCR	12 (80.0)	4 (33.3)	15 (100.0)		12 (100.0)
Wantai	2 (13.3)	8 (66.7)	0 (0.0)		0 (0.0)
Days after infection sampled (median [IQR])	294.00 [237.00, 426.50]	91.50 [90.25, 95.75]	108.00 [95.50, 127.00]	<0.001
Recovered = Yes (%)	0 (0.0)	12 (100)	7 (46.7)		0 (0.0)a
Infection before vaccination = Yes (%)	15 (100.0)	12 (100.0)	15 (100.0)	>0.99	12 (100.0)
Residual symptoms = Yes (%)	15 (100.0)	0 (0)	8 (53.3)
Days of hospitalization (median [IQR])	0 (0)	0 (0)	9.00 [6.00, 11.50]		12.5 [9.75, 16.00]
ICU admission = Yes (%)	0 (0)	0 (0)	5 (33.3)		12 (100.0)
Intubation = Yes (%)	0 (0)	0 (0)	2 (14.3)		12 (100.0)

The fatal/severe patients have been described in reference 6, and were just added for comparison and not included in the statistical analyses. n.k.: not known.

Parametric quantitative variables are presented as means of standard deviation (SD), and nonparametric quantitative variables are presented as median and interquartile ranges (IQR; 25th and 75th percentiles).

Categorical data were analyzed using a chi-square test. Continuous parametric data were analyzed using analysis of variance. Continuous non-parametric data were analyzed using the Kruskal–Wallis H test.

^a10 deaths, 1 unknown after transfer, 1 not recovered after 3 months.