Table 1.
Clinical characteristics of AIS/MIA and LUAD among pGGO, mGGO and solid nodule in our study cohort (n = 197).
| Clinical variable | AIS/MIA |
AIS/MIA |
AIS/MIA |
P | LUAD |
LUAD |
LUAD |
P |
|---|---|---|---|---|---|---|---|---|
| pGGO (n = 67) | mGGO (n = 30) | Solid (n = 1) | pGGO (n = 3) | mGGO (n = 32) | Solid (n = 64) | |||
| Sex, n (%) | 1 | 0.22 | ||||||
| Female | 46 (68.7) | 21 (70.0) | 1 (100.0) | 2 (66.7) | 20 (62.5) | 30 (46.9) | ||
| Male | 21 (31.3) | 9 (30.0) | 0 (0.0) | 1 (33.3) | 12 (37.5) | 34 (53.1) | ||
| Age, n (%) | 0.36 | 0.42 | ||||||
| ≤60 | 46 (68.7) | 17 (56.7) | 1 (100.0) | 1 (33.3) | 15 (46.9) | 23 (35.9) | ||
| >60 | 21 (31.3) | 13 (43.3) | 0 (0.0) | 2 (66.7) | 17 (53.1) | 41 (64.1) | ||
| Smoking, n (%) | 0.97 | 0.14 | ||||||
| Never | 51 (76.1) | 22 (73.3) | 1 (100.0) | 2 (66.7) | 26 (81.2) | 41 (64.1) | ||
| Ever | 16 (23.9) | 8 (26.7) | 0 (0.0) | 1 (33.3) | 6 (18.8) | 23 (35.9) | ||
| Histology, n (%) | – | <0.05 | ||||||
| Lepidic | / | / | / | 2 (66.7) | 9 (28.1) | 3 (4.7) | ||
| Acinar | / | / | / | 1 (33.3) | 17 (53.1) | 40 (62.5) | ||
| Papillary | / | / | / | 0 (0.0) | 6 (18.8) | 10 (15.6) | ||
| Solid | / | / | / | 0 (0.0) | 0 (0.0) | 9 (14.1) | ||
| IMA | / | / | / | 0 (0.0) | 0 (0.0) | 2 (3.1) | ||
| P stage, n (%) | 0.32 | 0.15 | ||||||
| AIS | 19 (28.4) | 5 (16.7) | 0 (0.0) | / | / | / | ||
| MIA | 48 (71.6) | 25 (83.3) | 1 (100.0) | / | / | / | ||
| IA | / | / | / | 3 (100.0) | 22 (68.7) | 31 (48.4) | ||
| IB | / | / | / | 0 (0.0) | 7 (21.9) | 20 (31.3) | ||
| IIIA | / | / | / | 0 (0.0) | 3 (9.4) | 13 (20.3) | ||
| Tumor size, n (%) | 0.27 | <0.05 | ||||||
| (0,1] | 47 | 21 | 1 | 1 | 4 | 2 | ||
| (1,2] | 13 | 3 | 0 | 2 | 18 | 21 | ||
| (2,3] | 2 | 1 | 0 | 0 | 8 | 25 | ||
| (3,6] | 0 | 0 | 0 | 0 | 2 | 16 | ||
| NA | 5 | 5 | 0 | 0 | 0 | 0 |
AIS, adenocarcinoma in situ; MIA, minimally invasive adenocarcinoma; LUAD, lung adenocarcinoma; GGO, ground-glass opacity; pGGO, pure ground-glass opacity; mGGO, mixed ground-glass opacity; IMA, invasive mucinous adenocarcinoma.