TABLE 1.
Plaque reduction-neutralization titers for YF/JE chimeras and parental viruses
| Virus | Result fora:
|
||||
|---|---|---|---|---|---|
| NI-AS | YF-AS | JE-AS | NI-IgG | YF-IgG | |
| YF5.2iv | <1.3 | 3.7 | <1.3 | <2.2 | >4.3 |
| JE SA14-14-2 | <1.3 | <1.3 | 3.4 | <2.2 | <2.2 |
| YF/JE-S | <1.3 | <1.3 | 3.1 | <2.2 | <1.9 |
| YF/JE-N | <1.3 | <1.3 | 3.4 | <2.2 | <2.2 |
| JE-N | <1.3 | <1.3 | 3.4 | <1.5 | <1.5 |
a
Values are the log reciprocal of the dilution yielding 50% neutralization, based on 100 PFU on LLC-MK2 cells. NI-AS, YF-AS, and JE-AS are nonimmune, YF hyperimmune, and JE hyperimmune ascitic fluids, respectively. NI-IgG and YF-IgG are purified Ig as described in Materials and Methods.