TABLE 2.
Neurovirulence analysis of YF/JE chimerasa
Virus | Dose (log10 PFU) | % Mortality (no. dead/no. tested) |
---|---|---|
YF5.2iv | 4 | 100 (7/7) |
YF/JE-S | 6 | 0 (0/8) |
5 | 0 (0/7) | |
4 | 0 (0/7) | |
YF/JE-N | 4 | 100 (5/5) |
3 | 100 (5/5) | |
2 | 100 (5/5) | |
1 | 60 (3/5) | |
0 | 0 (0/5) |
ICR mice (4 weeks old) received YF5.2iv, YF/JE-S, or YF/JE-N at the indicated doses by intracerebral inoculation.