TABLE 1.
Clinical information of SA-AKI patients before PSM and after PSM.
| Before PSM | After PSM | |||||||
|---|---|---|---|---|---|---|---|---|
| All patients (n = 12,091) | Non-users (n = 5,878) | Aspirin users (n = 6,213) | p | All patients (n = 7,694) | Non-users (n = 3,847) | Aspirin users (n = 3,847) | p | |
| Age (years) | 68.59 (57.16.79.38) | 63.53 (51.70.76.31) | 72.19 (62.79.81.00) | <0.001 | 69.25 (58.81.79.74) | 68.81 (58.03.80.24) | 69.56 (59.77.79.28) | 0.273 |
| Gender [male, n (%)] | 6,939 (57.4) | 3,208 (54.6) | 3,731 (60.1) | <0.001 | 4,331 (56.3) | 2,157 (56.1) | 2,174 (56.5) | 0.696 |
| Ethnicity, n (%) | ||||||||
| White | 7,975 (66.0) | 3,723 (63.3) | 4,252 (68.4) | <0.001 | 5,040 (65.5) | 2,518 (65.5) | 2,522 (65.6) | 0.292 |
| Yellow | 295 (2.4) | 157 (2.7) | 138 (2.2) | 184 (2.4) | 104 (2.7) | 80 (2.1) | ||
| Black | 975 (8.1) | 514 (8.7) | 461 (7.4) | 674 (8.8) | 327 (8.5) | 347 (9.0) | ||
| Other | 2,846 (23.5) | 1,484 (25.2) | 1,362 (21.9) | 1796 (23.3) | 898 (23.3) | 898 (23.3) | ||
| Heart rate (bpm) | 85.93 (75.92.98.27) | 89.73 (77.71,102.72) | 83.12 (74.67.93.35) | <0.001 | 86.13 (75.68.98.00) | 86.50 (75.32.98.64) | 85.85 (76.13.97.19) | 0.735 |
| Systolic pressure (mmHg) | 112.83 (104.67,123.88) | 113.31 (104.34,125.71) | 112.47 (104.95,122.34) | 0.006 | 113.34 (104.70,125.62) | 113.40 (104.40,125.91) | 113.24 (104.97,125.09) | 0.829 |
| Diastolic pressure (mmHg) | 60.04 (54.10.66.90) | 61.70 (55.56.68.96) | 58.47 (52.83.64.82) | <0.001 | 60.43 (54.48.67.18) | 60.56 (54.62.67.28) | 60.33 (54.33.67.12) | 0.493 |
| SpO2 (%) | 97.40 (95.88.98.70) | 97.24 (95.68.98.68) | 97.54 (96.04.98.73) | <0.001 | 97.31 (95.78.98.67) | 97.28 (95.75.98.68) | 97.34 (95.83.98.66) | 0.627 |
| Comorbidities, n (%) | ||||||||
| Diabetes mellitus | 3,954 (32.7) | 1,508 (25.7) | 2,446 (39.4) | <0.001 | 2,535 (32.9) | 1,243 (32.3) | 1,292 (33.6) | 0.235 |
| Hypertension | 3,568 (29.5) | 1,504 (25.6) | 2064 (33.2) | <0.001 | 2,292 (29.8) | 1,140 (29.6) | 1,152 (29.9) | 0.765 |
| Cardiac surgery | 5,122 (42.4) | 1,576 (26.8) | 3,546 (57.1) | <0.001 | 2,792 (36.3) | 1,378 (35.8) | 1,414 (36.8) | 0.393 |
| Therapy, n (%) | ||||||||
| RRT | 1,565 (12.9) | 779 (13.3) | 786 (12.7) | 0.324 | 998 (13.0) | 494 (12.8) | 504 (13.1) | 0.734 |
| Vasoactive drug | 7,466 (61.7) | 3,223 (54.8) | 4,243 (68.3) | <0.001 | 4,523 (58.8) | 2,244 (58.3) | 2,279 (59.2) | 0.418 |
| Mechanical ventilation | 11,633 (96.2) | 5,574 (94.8) | 6,059 (97.5) | <0.001 | 7,416 (96.4) | 3,700 (96.2) | 3,716 (96.6) | 0.328 |
| laboratory index | ||||||||
| Urine output (ml) | 1,425.00 (850.00,2135.00) | 1,365.00 (788.75,2105.35) | 1,470.00 (903.00,2150.00) | <0.001 | 1,373.50 (820.00,2090.50) | 1,353.00 (799.00,2055.00) | 1,400.00 (841.00,2125.00) | 0.068 |
| Hemoglobin (g/dL) | 9.70 (8.20.11.40) | 9.90 (8.30.11.60) | 9.50 (8.20.11.10) | <0.001 | 9.90 (8.40.11.50) | 9.90 (8.30.11.60) | 9.80 (8.40.11.40) | 0.695 |
| White blood cell (× 109/L) | 10.00 (7.10.13.50) | 10.00 (6.70.13.80) | 10.00 (7.40.13.20) | 0.089 | 10.10 (7.10.13.60) | 10.00 (6.90.13.70) | 10.20 (7.40.13.60) | 0.007 |
| Platelets (× 109/L) | 161.00 (109.00,225.00) | 163.00 (103.00,232.00) | 159.00 (114.00,218.00) | 0.430 | 169.00 (114.00,232.00) | 169.00 (111.00,233.00) | 168.00 (117.00,231.00) | 0.234 |
| Glucose (mg/dL) | 114.00 (95.00,137.00) | 112.00 (93.00,136.00) | 116.00 (98.00,139.00) | <0.001 | 115.00 (96.00,140.00) | 115.00 (95.00,139.00) | 116.00 (97.00,140.00) | 0.196 |
| Prothrombin time s) | 13.70 (12.30.15.40) | 14.00 (12.30.16.30) | 13.50 (12.20.15.13) | <0.001 | 13.70 (12.20.15.50) | 13.80 (12.20.15.80) | 13.60 (12.30.15.20) | 0.017 |
| GCS score | 12.00 (8.00.14.00) | 11.0 (7.00.14.00) | 13.00 (8.00.14.00) | <0.001 | 12.00 (7.00.14.00) | 12.00 (7.00.14.00) | 12.00 (7.00.14.00) | 0.777 |
| SOFA score | 7.00 (5.00.10.00) | 7.00 (5.00.11.00) | 7.00 (5.00.9.00) | <0.001 | 7.00 (5.00.10.00) | 7.00 (4.00.10.0 | 7.00 (5.00.10.0 | 0.078 |
| AKI stage; n (%) | ||||||||
| 1 | 2,167 (17.9) | 1,018 (17.3) | 1,149 (18.5) | <0.001 | 1,272 (16.5) | 661 (17.2) | 611 (15.9) | 0.195 |
| 2 | 5,614 (46.4) | 2,582 (43.9) | 3,032 (48.8) | 3,600 (46.8) | 1767 (45.9) | 1833 (47.6) | ||
| 3 | 4,310 (35.6) | 2,278 (38.8) | 2032 (32.7) | 2,822 (36.7) | 1,419 (36.9) | 1,403 (36.5) | ||
Note: The Chi-square test was used to compare categorical variables, and the Wilcoxon rank-sum test was used for continuous variables.