FIG. 8.

RANTES mRNA expressed in rat brains following MV infection. Lewis rats, 21 to 24 days old, were infected with 4 × 10³ TCID₅₀ of the MV CAM/RB strain by intracerebral inoculation as described elsewhere (26). (A) Brain tissues obtained 3 to 13 days postinfection were examined for the expression of murine RANTES and MV nucleocapsid mRNAs by Northern blotting using total RNA isolated from the tissue (20 μg of RNA/lane). IP-10 mRNA induced by MV is shown for comparison, and aldolase A was used for normalization. (B) Quantitation of the mRNA bands is shown as a histogram.