Table 2.
Definition of comorbidities
| Hospital discharge code: ICD-9-CM (in the last 5 years) | Exemptions code | Pharmacy claim code: ATC (in the last 12 months) | |
| Chronic pulmonary disease | 480–488; 491; 495; 518.81–518.84 | 024 | J05AH |
| Chronic obstructive pulmonary disease* | 490; 492; 494; 496 | 057 | R03 |
| Asthma* | 493 | 007 | – |
| Cardiovascular and cerebrovascular diseases | 390–398; 406–459 | 002; 021; 0A02; 0B02; 0C02; 036 | B01AC; C01B; C01DA; C08DA; C08DB |
| Hypertension | 401–405 | 031; 0A31 | C02; C03; C07; C08; C09 |
| Chronic kidney diseases | 580; 582–585; 593; 753.12–753.14 | 023; 022; 061; 062 | – |
| Dementia/Alzheimer’s disease | 290; 294.1; 331.2 | 011; 029 | N06DA; N06DX |
| Diabetes | 250 | 013 | A10 |
| Rheumatic diseases | 446.5; 696; 710; 714; 720; 725 | 006; 028; 030; 045; 054; 067 | L04 |
| Haematological disease | 280–289 (excl. 285.1) | 003 | B01AA; B01AB; B01AE; B01AF; B01AX; B02BD; B03 |
| Neurological diseases | 238.7; 296.3; 311; 332; 345; 340; 348.39 | 017; 038; 044; 046 | N03A; N04B; N05A; N06A |
| Neoplasms | 140–209; V10 | 048 | L01 |
| Metabolic disorders | 272; 278 | 025 | C10 |
| Moderate/severe hepatopathy | 456.0–456.2; 571–572; 573.0 | 008; 016 | – |
| Cystic fibrosis | 277.0 | 018 | R07AX |
| Ulcer disease | 531; 532; 533 | A02B | |
| Colitis | 555; 556 | 009 | – |
| HIV | 042 | 020 | J05AE; J05AF; J05AG; J05AR |
| Infections* | 053; 599.0; 010–018; 031; 078.5; 052–054; 136.3; 117.5 | 055 | J01; J02; J04; J05 (excl. J05AE; J05AF; J05AG; J05AH; J05AR) |
*ICD-9-CM in 365 days.
ATC, Anatomical Therapeutic Chemical; HIV, Human Immunodeficiency Virus; ICD-9-CM, International Classification of Diseases, Ninth Revision, Clinical Modification.