Table 3.

Consequences of fatigue reported by included reviews

ICF-model component			RA	SpA	OA	FM
Functional perspective	Body function and structure	Pain	X*		X*
		Disease activity/severity	X*	X*
		Fatigue	X†
		Overall health/health-related quality of life	X	X	X
		Depression	X*	X*	X*
		Sleep (disturbances)			X*
	Activities	Physical functioning‡	X*†
		Physical activity‡	X*†	X†	X*
		Physical impairment/disability‡			X*
		Sexual activities	X
	Participation	Work performance	X†	X	X
		Social activities and household chores	X*		X
		Role limitations (general)	X*
		Daily self-care and socially relevant tasks	X
Contextual perspective	Personal factors	Stress	X*†
		Parenting and family size	X†
		Physical and mental or emotional well-being	X*
		Coping	X*
	Environmental factors	Social support	X*†
		Partner relationships	X
		Relational and socioeconomic variables	X*†

*Also reported as determinants for fatigue by included reviews.

†Reported in at least one systematic review, excluding those that were unclear as to whether variable was considered a determinant or consequence.

‡Conceptual difference between these consequences was not clear based on the reviews.

FM, fibromyalgia; ICF, International Classification of Functioning; OA, osteoarthritis; RA, rheumatoid arthritis; SpA, spondyloarthritis.