Table 2.
MRI Protocol in the Second (First Follow-Up) Survey.
| Sequence (Data type) | Measured property and commentary | Sequence parameters | ||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Acquisition & slice | TR (ms) | TE (ms) | Inversion time (ms) | SENSE: AP RL |
b-value (s/mm2) | FOV (mm) | Matrix | Slice thickness (mm) | FA (degrees) | Acquisition time (s) | ||
| T1-weighted imaging (T1WI) (29) | Brain structures obtained by magnetization prepared-rapid gradient echo (MP-RAGE) | 3D Sagittal |
11 | 5.2 | 1068.3 | 2 2.5 |
N/A | 256 | 368 × 368 | 0.7 | 8 | 319 |
| Magnetic resonance angiography (MRA) (30) | Brain vascular structure | 3D Axial |
25 | 3.5 | 0 | 1(FH) 3 |
N/A | 200 | 384 × 249 | 1.1 | 18 | 247 |
| Diffusion tensor imaging (DTI) (31) | Interaction or connection of white matter fascicles in the brain | 2D Axial |
7173 | 83 | 0 | 2.5 N/A |
800 | 224 | 112 × 112 | 2 | 90 | 318 |
| Pseudo-continuous arterial spin-labeling (pCASL) (32) | Cerebral blood flow1, | 2D Axial |
4148 | 11 | 0 | 2.1 N/A |
N/A | 240 | 64 × 64 | 7/1 | 90 | 247 |
| Fluid-attenuated inversion recovery (FLAIR) (33) | White matter lesions | 3D Sagittal |
4800 | 276 | 1650 | 3 3.2 |
N/A | 256 | 212 × 212 | 1.2 | 90 | 264 |
| Neurite orientation dispersion and density imaging (NODDI) (35) | Microstructure of neurites (i.e., axons and dendrites) | 2D Axial |
7278 | 111 | N/A | 3 N/A |
711 (30)2 2855 (60)2 |
230 | 112 × 109 | 2.5 | 90 | 944 |
| Resting state-functional-MR imaging (Rs-fMRI): Protocol 1 (36) | Functional connectivity | 2D Axial |
3000 | 30 | N/A | 3 N/A |
N/A | 224 | 76 × 73 | 3 | 90 | 372 |
| Rs-fMRI: Protocol 2 (37) | Functional connectivity | 2D Axial |
2500 | 30 | N/A | N/A N/A |
N/A | 212 | 64 × 63 | 3.2 | 80 | 612 |
| T2-weighted imaging | White matter lesions | 2D Axial |
4134 | 100 | N/A | N/A 2 |
N/A | 230 × 221 | 384 × 269 | 5/1 | 90 | 157 |
| T2*-weighted imaging (38) | Cerebral microbleeds | 2D Axial |
664 | 18 | N/A | N/A 2 |
N/A | 230 × 217 | 304 × 229 | 5/1 | 18 | 78 |
| Susceptibility-weighted imaging (SWI) (38) | Cerebral microbleeds | 3D Axial |
31 | 7.2 | N/A | (FH) 1.5 3 |
N/A | 230 × 189 | 384 × 316 | 2 | 17 | 181 |
Notes:
Parenthesized numerical references correspond to bibliographic citations elsewhere in the manuscript.
TR: repetition time, TE: echo time, SENSE: sensitivity encoding, FOV: field of view, FA: flip angle.
D: Dimension, AP: anterior and posterior directions, RL: right and left directions, FH: foot and head direction
N/A: Not applicable
TR, TE, and Inversion time could be variable according to the slice angle.
1 Post-labeling delay: 1,800 ms
2 The number in the parenthesis is the number of diffusion directions.