Table 2. Univariable and multivariable analyses of preoperative prognostic factors for overall survival in all patients.
| Variables | Univariable | Multivariable | |||
|---|---|---|---|---|---|
| Hazard ratio (95% CI) | P | Hazard ratio (95% CI) | P | ||
| Age, years | 1.166 (1.040–1.368) | 0.005 | 1.116 (0.978–1.358) | 0.113 | |
| Sex (male) | – | – | |||
| PS [1] | 9.995 (1.421–46.976) | 0.025 | 2.882 (0.290–26.254) | 0.347 | |
| FEV1% (<70%) | 1.523 (0.499–4.782) | 0.455 | |||
| CEA (>5.0 ng/mL) | 3.010 (0.643–10.825) | 0.146 | |||
| CYFRA (>3.5 ng/mL) | 4.682 (1.018–16.363) | 0.048 | 0.890 (0.109–4.374) | 0.898 | |
| SCC (>2.5 ng/mL) | 1.910 (0.507–6.104) | 0.314 | |||
| SUVmax | 1.013 (0.922–1.105) | 0.770 | |||
| VDT | 0.986 (0.974–0.994) | <0.001 | 0.990 (0.979–0.997) | 0.002 | |
CI, confidence interval; PS, performance status; FEV1, forced expiratory volume in the first second; CEA, carcinoembryonic antigen; CYFRA, cytokeratin 19 fragment; SCC, squamous cell carcinoma antigen; SUVmax, maximum standardized uptake value; VDT, tumor volume doubling time.